|
Table of Contents Class
Review: Chromatographic FT-IR and Raman Spectroscopy **
MCF's 21st Annual Spring Symposium ** Course Review: Chromatographic FT-IR Raman Spectrometric Methods William Cameron On February 16 and 17, Dr. James de Haseth presented a short course on chromatographic methods interfaced to vibrational spectrometry. At the joint urgings of the MCF and SAS - who represent two types of analytical chemists - Dr. de Haseth taught this course which blended the disciplines of spectroscopy and chromatography. Twenty students representing nine different companies (with various levels of expertise in the areas of chromatography, spectroscopy, and the combination of the two) were treated to a course covering a wide-range of topics. Dr. de Haseth, a professor at the University of Georgia, covered topics which included: an introduction to vibrational spectroscopy, spectral search systems, CE-FTIR, GC-FTIR, LC-FTIR, SFC-FTIR, evolved gas analysis using FTIR, Thin-Layer FT-IR and Raman, and Isotachophoresis/Raman. His expertise in the area of vibrational spectrometric detectors which are connected and tagged to separation techniques was displayed throughout the course. His enthusiasm was demonstrated as he helped students apply the lessons learned in 'academia' to their real-life samples and problems. Note: This class had originally been scheduled for last year's Spring Symposium but was cancelled because of a major allergy attack last spring. Dr. de Haseth was very kind to return during Minnesota's low allergy season. Our hearty thanks to Jim for a job well done!!!
Course Review: Introduction to HPLC William Cameron On January 25th - 27th, 2000, MCF offered a three day course titled "Introduction to High Performance Liquid Chromatography". The course was co-presented by Dr. David Johnson of 3M and Dr. Larry Felice of Medtox and held at the University of Minnesota, St. Paul Campus. This course was last offered two years ago, and the strong interest in its re-offering was illustrated by how quickly it filled. The first day of the course consisted of lectures that covered chromatographic theory, column chemistry, and system concerns. The second day was a series of laboratory exercises giving the class an opportunity to adjust LC parameters and observe how the chromatography would be effected. The third day was back in the classroom with practical discussions on such topics as; sample prep, method development, and maintenance. Our thanks to David and Larry for putting together this class and their enthusiasm in its presentation. In addition, we thank the vendors (Steve Brown of Agilent, David Peterson of Beckman, Steve and Michelle Pierson of ChromTech/Thermoquest, Kevin Tyvoll of Perkin Elmer, Tom Genslak of Shimadzu, Ed Weir of VWR, and Mike Woodman of Waters) for providing equipment, supplies, and support which made the laboratory section of this course possible. WANTED: Guest Columnists Do you have a new chromatography technique or process? Do you have tips that could help others? Please share! Be a MCF Newsletter Guest Columnist! We are looking for innovative ideas in the chromatographic field. Please share your experiences/ideas to help your colleagues. Send your submissions via e-mail or fax to a MCF Newsletter Committee Member listed below: carrie.berge@ch.novartis.com
(f) 612 591-2941 MCF Spring Symposium Short Courses May 16th – 17th, 2000 Fundamentals of Size Exclusion
Chromatography and Related Polymer Separation Techniques Mass Spectral Interpretation Troubleshooting Gas
Chromatography Systems - Getting the Best Results from Your Gas
Chromatograph 21st Annual MCF Spring Symposium / Course Registration Form Call For Palmer Award Nominations The Minnesota Chromatography Forum (MCF) presents the Palmer Award annually at the Spring Symposium. The award recognizes one individual for their contributions to the art and science of chromatography during the previous year. Past recipients have included internationally recognized chromatographers as well as long-term MCF volunteers. Many people wonder about the Palmer Award and who is eligible to receive it. This may answer some of those questions. What is the Palmer Award? How is the Palmer Award winner selected? Who can receive the award? How can I nominate someone?
**********GUEST COLUMNIST********* Thomas K. Chambers, 3M
Pharmaceuticals, and HPLC/FTIR combines the components of a liquid chromatograph with an FTIR bench through a specialized interface. It is not an on-line IR detector for HPLC. Instead, the effluent from the chromatograph is fed to a heated nebulizer where the mobile phase is removed via matrix elimination. In a manner similar to thermospray, the liquid effluent of the HPLC is evaporated as analytes are transported away from the nebulizer by a stream of gas. The flow of gas is directed toward a rotating germanium disc. The analytes deposit as solids on the surface of the germanium and are saved for interrogation on an FTIR instrument. The LC-Transform instrument consists of the post-column interface described above plus an optics module that fits directly into the sample compartment of an FTIR. Infrared energy is focused through the sample deposit on the aluminum-backed germanium disc and is then reflected back through the sample to the detector. The disc is rotated to interrogate the entire chromatogram. Infrared spectra can be generated for specific positions (peaks) in the sample deposit, or the chromatogram can be reconstructed using total IR absorbance or absorbance along a band associated with a specific functional group, such as a carbonyl. One advantage of this technique is that the IR signal-to-noise can be greatly increased by positioning a segment of the sample deposit under the IR beam and acquiring multiple scans. Such signal-to-noise enhancement could not be achieved in an on-line HPLC/FTIR experiment. FTIR spectra can be assembled in 3-dimensional multi-file sets, which can provide valuable information about the identity and purity of the sample. One of the greatest advantages of the technique is the capability to obtain FTIR data from a sample mixture. In this way, costly isolation and sample preparation steps can be avoided.
21st Annual Spring Symposium Call For Papers ABOUT THE SYMPOSIUM The Keynote Speaker will be Dr. Art Moseley from Glaxo Wellcome, Inc. His topic will be "Nano-Scale Capillary LC-MS-MS for Proteomic Characterization". This Call for Papers solicits contributions for oral and poster presentations from all areas of separation science. If your group has made interesting progress in chromatography, this is an excellent opportunity to share your work with your peers. ABSTRACT SUBMISSIONS VIA WEBSITE ABSTRACT SUBMISSIONS By mail (on paper or diskette) to: By FAX to Janice Jopke at (612) 934-6741 By e-mail to Peter Johnson at prjohnson1@mmm.com All of the information which is requested on the Abstract Information Form must be included. The work must be presented by a person who was directly involved in the research. Plan your presentation to be no longer than fifteen minutes followed by a 5-minute question and answer period. The deadline for abstract submission is March 31, 2000. Spring Symposium Calendar of Events
|
|||||||||||||||||
