Use of Designed Experiments in Chromatography

February 5-7, 2002 ...

Tentative Agenda:

Day One:
Introduction and overview of Designed Experiments (DOE) 
Comparison of DOE with traditional one variable at a time (OVAT) experiments 

Day Two:
Further investigation into 2^3 Factorial DOE’s as applied to chromatography (3 factor & 4-7 factor design) 
Understanding of the basic statistics behind DOE 
Specific examples (method development, troubleshooting)

Day Three:
Discussion of available software used for designed experiments 
DOE vs. other experimental designs in chromatographic apps. 
Setting up DOE’s using participant’s examples 
Some simple advanced applications

For class information, contact Jan Jopke, at (952) 949-2518. 

To register for the course, complete the website registration form and send it with a check for $(contact Jan), payable to the Minnesota Chromatography Forum.

Note:
If confirmation is not received within 10 business days, contact Jan at (952) 949-2518. Please bring confirmation to first day of class.

Meet the Instructor …

Lars A. Pekay, Ph.D., is currently the Quality & Regulatory Manager for General Mills in Lodi, CA. He received his B.S. in Chemistry from Wake Forest University in North Carolina and an M.S. and Ph.D. in Analytical Chemistry from The Ohio State University. His graduate work focused on the development and characterization of sulfur specific detectors for supercritical fluid chromatography to monitor the effectiveness of a proprietary method of coal desulfurization.  During his tenure at General Mills, Lars has worked on both HPLC and GC method development, extensive training on both analytical methods and applied statistics, vitamin processing research, and on the development of a certification program to decrease analytical variability. He has been heavily involved with the use of Designed Experiments, both for analytical applications and as applied to production issues (during the past year, using a series of DOE’s, production efficiency on a start-up line in Lodi went from 65% to 98%). He is also an American Society of Quality Control Certified Auditor and has served on the Minnesota Chromatography Forum board and symposium committees and has served as the MCF president in the past.